You have accessJournal of UrologyCME1 Apr 2023MP19-19 PRIORITIZED RESEARCH QUESTIONS ON THE USE OF ACTIVE SURVEILLANCE FOR THE MANAGEMENT OF PROSTATE CANCER: RESULTS FROM PCASRI CONFERENCE Shu Wang, Michelle Medeiros, Michael Rothberg, Ryan Russell, Zach Kozel, Tony Crispino, Joseph Gallo, Mark Lichty, Alexandra Scholz, Jimmie Slade, Judi Wolinsky, Howard Wolinsky, Arvin George, Jim Hu, Howard Parnes, Christian Pavlovich, Peter Pinto, Sanoj Punnen, Christopher Saigal, Samuel Washington, Kara Watts, Caroline Moore, Daniel Mullins, Michael Scott, and M. Minhaj Siddiqui Shu WangShu Wang More articles by this author , Michelle MedeirosMichelle Medeiros More articles by this author , Michael RothbergMichael Rothberg More articles by this author , Ryan RussellRyan Russell More articles by this author , Zach KozelZach Kozel More articles by this author , Tony CrispinoTony Crispino More articles by this author , Joseph GalloJoseph Gallo More articles by this author , Mark LichtyMark Lichty More articles by this author , Alexandra ScholzAlexandra Scholz More articles by this author , Jimmie SladeJimmie Slade More articles by this author , Judi WolinskyJudi Wolinsky More articles by this author , Howard WolinskyHoward Wolinsky More articles by this author , Arvin GeorgeArvin George More articles by this author , Jim HuJim Hu More articles by this author , Howard ParnesHoward Parnes More articles by this author , Christian PavlovichChristian Pavlovich More articles by this author , Peter PintoPeter Pinto More articles by this author , Sanoj PunnenSanoj Punnen More articles by this author , Christopher SaigalChristopher Saigal More articles by this author , Samuel WashingtonSamuel Washington More articles by this author , Kara WattsKara Watts More articles by this author , Caroline MooreCaroline Moore More articles by this author , Daniel MullinsDaniel Mullins More articles by this author , Michael ScottMichael Scott More articles by this author , and M. Minhaj SiddiquiM. Minhaj Siddiqui More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003244.19AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Active surveillance (AS) is recommended for the management of favorable-risk prostate cancer (PCa) to avoid the harmful effects of overtreatment. Rates of utilization of AS in the US however remain suboptimal due to multi-factorial issues. We sought to engage a diverse group of patients, patient advocates, researchers and clinicians to better understand the current shortcomings in AS implementation, as well as develop a patient-engaged list of research priorities for PCa AS. METHODS: We organized a 2-day conference, Developing Provocative Questions-PCa AS Research Initiative (PCASRI). Through small groups consisting of physicians, patients and families, researchers, and advocates we discussed twelve selected topics in four domains following the PICOTS criteria (Population, Intervention, Outcome, and Setting). Through an iterative process, we generated and then ranked meaningful PCa AS research questions from all participants. Ultimately, eight prioritized questions were selected and ranked through voting. RESULTS: A total of 152 people participated over the 2-day conference with 45.5% patients with PCa, 29.5% urologists, and the remainder a mix of supporters, advocates, and researchers. Eight questions were prioritized out of 22 initially generated. The number one research priority that emerged after this process was “How do we incorporate imaging for improved AS of favorable-risk PCa patients”. The remainder of the 8 research priority topics in order of priority were 2: use of focal therapy to augment AS, 3: risk-specific personalized follow-up intensity for AS, 4: use of telemedicine vs in-person support groups to address disparities in PCa AS utilization, 5: impact of micro-ultrasound vs MRI for AS of PCa, 6: optimal integration of imaging and genomic biomarkers for AS, 7: integration of health educators to improve uptake of AS, and 8: impact of HIIT exercise on PCa AS. CONCLUSIONS: We generated a multi-stakeholder engaged process to identify research priorities in improving uptake of AS in the appropriate risk PCa population. The top priority identified was optimal integration of MRI in AS follow-up processes. Continued research in these priority areas combined with continued patient and multi-stakeholder engagement may provide meaningful patient-centered impact on the use of AS. Source of Funding: This project was funded through a Patient-Centered Outcomes Research Institute (PCORI) Eugene Washington PCORI Engagement Award (EAIN-19842). © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e273 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Shu Wang More articles by this author Michelle Medeiros More articles by this author Michael Rothberg More articles by this author Ryan Russell More articles by this author Zach Kozel More articles by this author Tony Crispino More articles by this author Joseph Gallo More articles by this author Mark Lichty More articles by this author Alexandra Scholz More articles by this author Jimmie Slade More articles by this author Judi Wolinsky More articles by this author Howard Wolinsky More articles by this author Arvin George More articles by this author Jim Hu More articles by this author Howard Parnes More articles by this author Christian Pavlovich More articles by this author Peter Pinto More articles by this author Sanoj Punnen More articles by this author Christopher Saigal More articles by this author Samuel Washington More articles by this author Kara Watts More articles by this author Caroline Moore More articles by this author Daniel Mullins More articles by this author Michael Scott More articles by this author M. 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